Chemotherapeutical medicines consumption (antiblastic therapies) has toxicity, often dose/ dependent, for our body. Quantity of medicine to use depends on the body constitution that is bodily mass measured in m2. There are two different ways to administer medicines: orally and intravenous injection.
Lately for some neoplastic pathology the most applied medicines administered orally are Capecitabine, Navelbine and Temozolomide. Anti-estrogens, anti-aromatase and anti-androgens are administered orally too. Anti-estrogens and anti-aromatase are used for mammary pathologies and anti-androgens for prostatic ones; mainly they are adjuvant in post-chemotherapy.
Capecitabine (trade name “Xeloda”) is mainly active in gastro enteric neoplasia (colon, stomach and bile ducts) and also in mammary neoplasia. Usually Capecitabine is a second choice, but with elderly and exhausted people it can be the first one. With young patients it can be used together with other antiblastic medicines.
Side effects such as epigastria, altralgie and some isolated rash skin are the result of many daily tablets. Navelbine can be taken per os. It can achieve positive effects in hepatic secondary lesions from primitive mammary to gastro enteric. In Navelbine too there are side effects as for example epigastria and bony pain.
Temozolomide (Temodal) is applied in brain tumors with good results in the combined application with radiotherapy. Actually there are studies on the employment of this medicine with Hyperthermia. Intravenous injection is used for all the antiblastic medicines through a port-a-cut or directly with cannula needle in vein. Measuring of the medicine is calculated on the patient body area (m2). Dose is usually administered in bolus. There is the possibility to fraction measuring in several times. This method is not universally accepted from the whole scientific community but it is used by Prof. Salem (Director of S. Luc Cancer Center of Houston- Texas). He practices the fractionation of antiblastic medicines and applies also an integrated complementary therapy. His results are unexpected.