Integrative Oncology Therapy Research Association
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Anti-VEGF drugs

Some drugs act by inhibiting angiogenesis, that is hindering the development of blood vessels that feed tumors and causing growth arrest and regression of tumors. The main mechanism of action of this class of drugs involves the angiogenesis growth factor (Vascular Endothelial Growth Factor or VEGF) and its receptor (VEGFR). Again, as we have seen for anti-EGFR there are basically two types of drugs: monoclonal antibodies that block the receptor or growth factor (intravenous) and small molecules which binds to the tyrosine kinase receptor determining the block.

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